Arş. Gör. ÖZLEM KAPLAN

Arş. Gör. ÖZLEM KAPLAN

Arş. Gör.
ÖZLEM KAPLAN

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Genel Bilgiler

Kurum Bilgileri

  • Kurum Bilgi RAFET KAYIŞ MÜHENDİSLİK FAKÜLTESİ, GENETİK VE BİYOMÜHENDİSLİK BÖLÜMÜ, GENETİK VE BİYOMÜHENDİSLİK ANABİLİM DALI
  • UnvanARAŞTIRMA GÖREVLİSİ

İletişim Bilgileri

  • Ofis GENETİK VE BİYOMÜHENDİSLİK BÖLÜMÜ
  • AdresRAFET KAYIŞ MÜHENDİSLİK FAKÜLTESİ, GENETİK VE BİYOMÜHENDİSLİK BÖLÜMÜ

Çalışma/ Uzmanlık Alanları

Biyonanoteknoloji

İlaç Salım Sistemleri

Kanser Genetiği

Rekombinant DNA Teknolojisi

Protein temelli nanopartiküler sistemler

Biyografi

Scopus Bilgiler

Scopus Citation-Count Scopus Cited-by-count Scopus Toplam Yayın Scopus Eid Değeri Scopus Orcid Değeri Scopus Link

Google Scholar Bilgiler

Google H-index Google i10-index Google H-index 2018 Google i10-index 2018 Google Atıf Google Atıf 2018

Araştırma Alanları

Biyoteknoloji

Nanoteknoloji

Moleküler Genetik

Eğitim Bilgileri

Eğitim Bilgileri

  • Doktora

    İSTANBUL ÜNİVERSİTESİ, FEN BİLİMLERİ ENSTİTÜSÜ, MOLEKÜLER BİYOLOJİ VE GENETİK (DR),

    2022 2016

  • Yüksek Lisans

    GAZİOSMANPAŞA ÜNİVERSİTESİ, FEN BİLİMLERİ ENSTİTÜSÜ, BİYOMÜHENDİSLİK (YL) (TEZLİ),

    2016 2014

  • Lisans

    GAZİOSMANPAŞA ÜNİVERSİTESİ, MÜHENDİSLİK VE DOĞA BİLİMLERİ FAKÜLTESİ, BİYOMÜHENDİSLİK BÖLÜMÜ,BİYOMÜHENDİSLİK PR.

    2014 2010

Yaptığı Tezler

  • MOLEKÜLER BİYOLOJİ VE GENETİK (DR)

    Antiapoptotik protein inhibitörü yüklü nanopartiküllerin kanser hücreleri üzerindeki etkileri

    PROF. DR. EMİNE ŞEKÜRE NAZLI ARDA ; DOÇ. DR. MEHMET KORAY GÖK , 2022
    2022 2016

  • BİYOMÜHENDİSLİK (YL) (TEZLİ)

    Viral tanı kitlerinin geliştirilmesi için moloney murine leukemia virus (MMLV) revers transkriptaz enziminin rekombinant olarak üretilmesi

    PROF. DR. İSA GÖKÇE , 2016
    2016 2014

  • BİYOMÜHENDİSLİK BÖLÜMÜ

    , 2014
    2014 2010

Yabancı Diller

  • İngilizce : 2024, YÖKDİL, 78,75000
    İngilizce : 2018, YÖKDİL, 88.75

Deneyimler

Akademik Unvanlar

  • ARAŞTIRMA GÖREVLİSİ

    ALANYA ALAADDİN KEYKUBAT ÜNİVERSİTESİ, MÜHENDİSLİK FAKÜLTESİ, ALANYA ALAADDİN KEYKUBAT ÜNİVERSİTESİ/MÜHENDİSLİK FAKÜLTESİ/GENETİK VE BİYOMÜHENDİSLİK BÖLÜMÜ/

    2016

  • ARAŞTIRMA GÖREVLİSİ

    GAZİOSMANPAŞA ÜNİVERSİTESİ, MÜHENDİSLİK VE DOĞA BİLİMLERİ FAKÜLTESİ, GAZİOSMANPAŞA ÜNİVERSİTESİ/MÜHENDİSLİK VE DOĞA BİLİMLERİ FAKÜLTESİ/BİYOMÜHENDİSLİK BÖLÜMÜ/BİYOMÜHENDİSLİK PR./

    2016 2014

Yönetimsel Görevler

Verilen Dersler

  • 2022-2023

    Ders Adı:Genetic Engineering Lab II Ders Saati: 4 , İngilizce,Lisans

Yayınlar & Eserler

MAKALELER

Escherichia coli as a versatile cell factory: Advances and challenges in recombinant protein production

İNCİR İBRAHİM,KAPLAN ÖZLEM Protein Expression and Purification,cilt.219, ss.-, 2024 (SCI-Expanded dergi )

Development of recombinant protein-based nanoparticle systems for inducing tumor cell apoptosis: In vitro evaluation of their cytotoxic and apoptotic effects on cancer cells

KAPLAN ÖZLEM,GÖK MEHMET KORAY,PEKMEZ MURAT,ERDEN TAYHAN SEÇİL,PABUCCUOĞLU SAADET KEVSER,GÖKÇE İSA,ARDA EMİNE ŞEKÜRE NAZLI Journal of Drug Delivery Science and Technology,cilt.95, ss.-, 2024 (SCI-Expanded dergi )

Molecular pathway of anticancer effect of next-generation HSP90 inhibitors XL-888 and Debio0932 in neuroblastoma cell line

KAPLAN ÖZLEM,GÖKŞEN TOSUN NAZAN Medical Oncology,cilt.41, ss.-, 2024 (SCI-Expanded dergi )

Escherichia coliin the production of biopharmaceuticals

İNCİR İBRAHİM,KAPLAN ÖZLEM Biotechnology and Applied Biochemistry,cilt., ss.-, 2024 (SCI dergi )

Enhancing gene delivery efficiency with amphiphilic chitosan modified by myristic acid and tertiary amino groups

EKER FİDAN Emine Büşra,BAL KEVSER,Şentürk Sema,KAPLAN ÖZLEM,DEMİR KAMBER,GÖK MEHMET KORAY International Journal of Biological Macromolecules,cilt.282, ss.-, 2024 (SCI dergi )

Green synthesis of silver nanoparticles using Macrolepiota procera extract and investigation of their HSP27, HSP70, and HSP90 inhibitory potentials in human cancer cells

ÖZGÜR AYKUT, KAPLAN ÖZLEM, GÖKŞEN TOSUN Nazan, TÜRKEKUL İBRAHİM, GÖKÇE İSA Particulate Science and Technology,cilt., ss.-, 2023 (SCI-Expanded dergi )

A Silver Compound with Potential Applications as an Anticancer, Antibacterial, Antifungal, and Anti‐Alzheimers Agent

KORKMAZ NESRİN, KISA DURSUN, KAPLAN ÖZLEM, GÖKŞEN TOSUN NAZAN, ÖZGÜR AYKUT, İMAMOĞLU RİZVAN, KARADAĞ AHMET Chemistry & Biodiversity,cilt.20, ss.-, 2023 (SCI-Expanded dergi )

Diacid esters of 1-dodecanol as new alternatives to solid-liquid phase change materials for solar heat storage systems

KAPLAN ÖZLEM, GÖKŞEN TOSUN NAZAN, GÖKÇE İSA, ALKAN CEMİL Energy Sources, Part A: Recovery, Utilization, and Environmental Effects,cilt.45, ss.-, 2023 (SCI-Expanded dergi )

Thiolated α-cyclodextrin: The likely smallest drug carrier providing enhanced cellular uptake and endosomal escape

KAPLAN ÖZLEM, Truszkowska Martyna, Kali Gergely, Knoll Patrick, Blanco Massani Mariana, Braun Doris Elfriede, Bernkop-Schnürch Andreas Carbohydrate Polymers,cilt.316, ss.-, 2023 (SCI dergi )

Synthesis and Characterization of Dicarboxylic Acid Esters of 1‐Hexadecanol for a Thermal Energy Storage Application Range of 50–55 °C

ALKAN CEMİL, GÖKŞEN TOSUN NAZAN, KAPLAN ÖZLEM Energy Technology,cilt., ss.-, 2023 (SCI dergi )

Efficacy of the greenly synthesized silver, copper, and nickel nanoparticles using Allium tuncelianum extract against Acanthamoeba castellanii

AYKUR MEHMET, GÖKŞEN TOSUN NAZAN, KAPLAN ÖZLEM, ÖZGÜR AYKUT Journal of Drug Delivery Science and Technology,cilt.89, ss.-, 2023 (SCI-Expanded dergi )

Synergistic induction of apoptosis in liver cancer cells: exploring the combined potential of doxorubicin and XL-888

KAPLAN ÖZLEM Medical Oncology,cilt.40, ss.-, 2023 (SCI-Expanded dergi )

Biosynthesis of Iron, Copper and Silver Nanoparticles Using Polygonum Cognatum and Tragopogon Porrifolius Extracts and Evaluation of Their Antimicrobial Potentials

KAPLAN ÖZLEM, GÖKŞEN TOSUN NAZAN Duzce Universitesi Bilim ve Teknoloji Dergisi,cilt.11, ss.-, 2023 (TR DİZİN dergi )

Optimizing the Synthesis of Folic Acid Conjugated Silver Nanoparticles by Box-Behnken Design to Target Breast Cancer Cells

SOYLU SAFA FURKAN, KA Zidan Ahmed, GÖKŞEN TOSUN NAZAN, KAPLAN ÖZLEM, GÖKÇE İSA ALKU Fen Bilimleri Dergisi, Alanya Alaaddin Keykubat University,cilt., ss.-, 2023 (ResearchBib dergi )

Optimization Studies of Mg/Al-NO3 Layered Double Hydroxide Nanoparticles by Hydrothermal Treatment

BAL KEVSER, ŞENTÜRK SEMA, KAPLAN ÖZLEM, GÖK MEHMET KORAY, PABUCCUOĞLU SAADET KEVSER ALKU Fen Bilimleri Dergisi, Alanya Alaaddin Keykubat University,cilt., ss.-, 2023 (ResearchBib dergi )

Evaluation of combined use of hsp90 inhibitor mpc-3100 and traditional cancer drug 5-fu on liver cancer cell lines

KAPLAN ÖZLEM Journal of scientific reports-A (Online),cilt., ss.60-69, 2023 (TR DİZİN dergi )

Recombinant Production of E. coli NAD+-dependent DNA ligase as a Target for Antibacterial Drug Discovery

KAPLAN ÖZLEM, İMAMOĞLU RİZVAN, GÖKÇE İSA KSÜ Tarım ve Doğa Dergisi,cilt.25, ss.19-24, 2022 (TR DİZİN dergi )

Green Synthesis of Silver Nanoparticles Using Schizophyllum commune and Geopora sumneriana Extracts and Evaluation of Their Anticancer and Antimicrobial Activities

GÖKŞEN TOSUN NAZAN, KAPLAN ÖZLEM, TÜRKEKUL İBRAHİM, GÖKÇE İSA, ÖZGÜR AYKUT PARTICULATE SCIENCE AND TECHNOLOGY,cilt.40, ss.801-811, 2022 (SCI-Expanded dergi )

Biosynthesis of silver nanoparticle using white propolis extract as a reduction agent and optimized by Box-Behnken design

GÖKŞEN TOSUN Nazan, KAPLAN ÖZLEM Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi,cilt., ss.-, 2022 (TR DİZİN dergi )

Biosynthesis and characterization of silver nanoparticles from Tricholoma ustale and Agaricus arvensis extracts and investigation of their antimicrobial, cytotoxic, and apoptotic potentials

KAPLAN ÖZLEM, GÖKŞEN TOSUN Nazan, İMAMOĞLU RİZVAN, TÜRKEKUL İBRAHİM, GÖKÇE İSA, ÖZGÜR AYKUT Journal of Drug Delivery Science and Technology,cilt., ss.-, 2022 (SCI-Expanded dergi )

Green synthesized silver nanoparticles with mushroom extracts of Paxina leucomelas and Rhizopogon luteolus induce ROS-Induced intrinsic apoptotic pathway in cancer cells

GÖKŞEN TOSUN Nazan, KAPLAN ÖZLEM, İMAMOĞLU RİZVAN, TÜRKEKUL İBRAHİM, GÖKÇE İSA, ÖZGÜR AYKUT Inorganic and Nano-Metal Chemistry,cilt., ss.-, 2022 (SCI-Expanded dergi )

A new approach to breast cancer therapy: targeted nanocarrier systems

GÖKŞEN TOSUN Nazan, KAPLAN ÖZLEM, ERDEN TAYHAN SEÇİL, ALKAN CEMİL, GÖKÇE İSA International Journal of Chemistry and Technology,cilt.6, ss.81-92, 2022 (TR DİZİN dergi )

POLYMER-BASED TRANSFECTION AGENTS USED IN CRISPR-CAS9 SYSTEM

İMAMOĞLU RİZVAN, KAPLAN ÖZLEM, GÖK MEHMET KORAY, GÖKÇE İSA Turk Doga ve Fen Dergisi, Bingol University,cilt.11, ss.151-156, 2022 (TR DİZİN dergi )

Recombinant production of Thermus aquaticus single-strand binding protein for usage as PCR enhancer

KAPLAN ÖZLEM, İMAMOĞLU RİZVAN, ŞAHİNGÖZ İskender, GÖKÇE İSA International Advanced Researches and Engineering Journal,cilt.5, ss.-, 2021 (TR DİZİN dergi )

Recombinant production and characterization of Aspergillus niger prolyl endopeptidase enzyme for gluten-free food production

ŞENOL BELMA, KAPLAN ÖZLEM, İMAMOĞLU RİZVAN, GÖKÇE İSA International Journal of Agriculture, Environment and Food Sciences,cilt., ss.-, 2021 (TR DİZİN dergi )

Microwave-assisted green synthesis of silver nanoparticles using crude extracts of Boletus edulis and Coriolus versicolor: Characterization, anticancer, antimicrobial and wound healing activities

KAPLAN ÖZLEM,GÖKŞEN TOSUN NAZAN,ÖZGÜR AYKUT,ERDEN TAYHAN SEÇİL,BİLGİN SEMA,TÜRKEKUL İBRAHİM,GÖKÇE İSA Journal of Drug Delivery Science and Technology,cilt.64, ss.1-8, 2021 (SCI-Expanded dergi )

Development of a Fluorescent Protein Based FRET Biosensor for Determination of Protease Activity

İNCİR İBRAHİM,KAPLAN ÖZLEM,BİLGİN SEMA,GÖKÇE İSA Sakarya University Journal of Science,cilt.25, ss.1235-1244, 2021 (TR DİZİN dergi )

Optimization of the green synthesis of silver nanoparticle with Box-Behnken design: Using Aloe vera plant extract as a reduction agent

GÖKŞEN TOSUN Nazan, KAPLAN ÖZLEM Sakarya University Journal of Science,cilt., ss.-, 2021 (TR DİZİN dergi )

Biosynthesis of silver nanoparticles from Teucrioside and investigation of its antibacterial activity

KAPLAN ÖZLEM, GÖKŞEN TOSUN Nazan Cumhuriyet Science Journal,cilt.42, ss.-, 2021 (TR DİZİN dergi )

The relationship between DIRAS1 gene and idiopathic generalized epilepsy in the Turkish population

KAPLAN ÖZLEM, PEKMEZ MURAT, AKINCI YASEMİN, ATAKLI HAYRUNİSA DİLEK, EREN Fulya, CEYHAN DİRİCAN Ayten, GÖZÜBATIK ÇELİK RABİA GÖKÇEN, BAŞTUĞ GÜL Zeynep, UR ÖZÇELİK EMEL, GÜL GÜNAY, Sarı Hüseyin, ÖZKARA ÇİĞDEM Gene Reports,cilt.23, ss.-, 2021 (E-SCI dergi )

Apoptosis Induced by Tarantula cubensis Crude Venom (Theranekron® D6) in Cancer Cells

GÖKŞEN TOSUN Nazan, KAPLAN ÖZLEM, ÖZGÜR AYKUT Revista Brasileira de Farmacognosia,cilt., ss.-, 2021 (SCI-Expanded dergi )

High-Level Production of MMLV Reverse Transcriptase Enzyme in Escherichia Coli

KAPLAN ÖZLEM, İMAMOĞLU RİZVAN, GÖKÇE İSA International Journal of Advances in Engineering and Pure Sciences,cilt.33, ss.-, 2021 (TR DİZİN dergi )

KONFERANS & SEMPOZYUM & HAKEMLİ KONGRE & ULUSAL TOPLANTI & BİLDİRİ KİTAPLARINDA YER ALAN YAYINLAR

Synthesis and Evaluation of Neopentyl Glycol Diacrylate-Based Poly (Beta Amino Ester) Nanoparticles as Potential Gene Delivery Vehicles KAPLAN ÖZLEM

International 8th Usbilim Health, Engineering And Applied Sciences Congress, Diyarbakır, TÜRKİYE , ss.-, 2024.11.28

Artemisinin and Cancer: A Molecular Docking Analysis Perspective KAPLAN ÖZLEM

6th International Eurasian Conference on Biological and Chemical Sciences, Ankara, TÜRKİYE , ss.-, 2023.10.13

Analyzing the Potential of Combined Therapy with Ganetespib and Curcumin in Osteosarcoma KAPLAN ÖZLEM

SIVAS II. International Conference on Scientific and Innovation Research, Sivas, TÜRKİYE , ss.-, 2023.09.15

Efficacy of green synthesis of nickel, copper and silver nanoparticles using Thymus serpyllum extract against Acanthamoeba castellanii AYKUR MEHMET, GÖKŞEN TOSUN NAZAN, KAPLAN ÖZLEM, ÖZGÜR AYKUT

1th International Congress on Solutions in Science (INSCORE), İzmir, TÜRKİYE , ss.-, 2023.09.11

Green Synthesized Iron Nanoparticles Induced Apoptotic Patways in Breast Cancer Lines by Inhihition of Heat Shock Proteins GÖKŞEN TOSUN Nazan, KAPLAN ÖZLEM, İMAMOĞLU RİZVAN, TÜRKEKUL İBRAHİM, GÖKÇE İSA, ÖZGÜR AYKUT

4rd Eurasia Biochemical Approaches & Technologies Congress (EBAT), Antalya, TÜRKİYE , ss.-, 2022.11.05

Green Synthesis of Silver Nanoparticles Using Armillaria Mellea and Xerocomellus Chrysenteron Extracts and Evaluation of Their Antimicrobial and Anticancer Potentials ÖZGÜR AYKUT, GÖKŞEN TOSUN NAZAN, KAPLAN ÖZLEM, TÜRKEKUL İBRAHİM, GÖKÇE İSA

3rd Eurasia Biochemical Approaches & Technologies Congress (EBAT), ANTALYA, TÜRKİYE , ss.-, 2021.11.10

Development of One-Step RT-PCR Kit for Diagnosis of COVID-19 GÖKÇE İSA, ÖZGÜR AYKUT, TAYHAN YAHYA, KAPLAN ÖZLEM, GÖKŞEN TOSUN NAZAN, İMAMOĞLU RİZVAN, ERDEN TAYHAN SEÇİL, BİLGİN SEMA

3rd Eurasia Biochemical Approaches & Technologies Congress (EBAT), ANTALYA, TÜRKİYE , ss.-, 2021.11.10

Expression purification and characterization of recombinant proteinase K from Tritirachium Album Limber İmamoğlu Rizvan,KAPLAN ÖZLEM,BİLGİN SEMA,GÖKÇE İSA

Pichia 2016, , , ss.-, 2016.04.06

Expression of Thermus aquaticus single strand binding protein in Pichia pastoris for molecular biology applications Şahingöz İskender,KAPLAN ÖZLEM,BİLGİN SEMA,ULUSU YAKUP

Pichia 2016, , , ss.-, 2016.04.06

Production of recombinant UnaG fluorescent protein in Pichia pastoris for Improving BILIRUBIN biosensor KAPLAN ÖZLEM,Bozkurt Yasemin,ULUSU YAKUP,GÖKÇE İSA

Pichia 2016, , , ss.-, 2016.04.06

Tanı Kitlerinin Geliştirilmesi İçin MMLV revers trasnkriptaz Enziminin Rekombinant Olarak Üretilmesi KAPLAN ÖZLEM

1. Yaşam Bilimleri Sempozyumu, , TÜRKİYE , ss.-, 2016.02.24

DNA Saflaştırma Kitlerinde Kullanmak İçin RNaz A Enziminin Rekombinant Olarak Üretilmesi, Saflaştırılması ve Karakterizasyonu İMAMOĞLU RİZVAN,KAPLAN ÖZLEM,GÖKÇE İSA

AGÜ II. Yaşam Bilimleri Kongresi, , TÜRKİYE , ss.-,

KİTAP & KİTAP BÖLÜMLERİ

Heat Shock Protein 90 Inhibitors and Combination Therapy Approach in Cancer KAPLAN ÖZLEM, GÖKŞEN TOSUN NAZAN

New Trends in Science and Mathematics, Hüsniye SAĞLIKER,Editör, Duvar Publishing , ss.497-516, 2022

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    Bilimsel Üyelikler & Hakemlikler

    BİLİMSEL ÜYELİKLER

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    Sanatsal Faaliyetler

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    Başarılar

    ÖDÜLLER

    • OKA BÖLGESEL İNOVASYON YARIŞMASI: PROJE PAZARI ETKİNLİĞİ

      2015

      Orta Karadeniz Kalkınma Ajansı

    • KTÜ-TTO Düşünden Gerçeğine Proje Pazarı Etkinliği

      2016

      KARADENİZ TEKNİK ÜNİVERSİTESİ

    • 2210-C Öncelikli Alanlara Yönelik Yurt Içi Yüksek Lisans Burs Programı

      2014

      TÜBİTAK

    • 2211-A Genel Yurt Içi Doktora Burs Programı

      2016

      TÜBİTAK

    • 2218-Yurt içi Doktora Sonrası Araştırma Burs Programı

      2022

    • Yayın Teşvik

      2023

    • Yayın Teşvik

      2023

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    • 2021 Yılı Atıf Sayısı :0

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